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Encyclopedia :
A :
AP :
APP :
Appel reaction |
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Appel reactionThe Appel reaction is a method to convert alcohols into halogenated compounds.The reagents used are Triphenylphosphine and a haloform (Chloroforme or Bromoforme). The reaction is based, like nearly all reactions containing phosphines and oxygen compounds (For example the Mitsunobu reaction), on the eliberation of triphenylphosphine oxide.
ReferenceLit. : R. Appel, Angew. Chem. Int. Ed., 1975, 14, 801-811
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